5-Aminoimidazole ribotide

5-Aminoimidazole ribotide
Names
	IUPAC name [5-(5-aminoimidazol-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
	Other names AIR,; [5-(5-amino-1-imidazolyl)-3,4-dihydroxy-2-tetrahydrofuranyl]methyl dihydrogen phosphate
Identifiers
CAS Number	25635-88-5 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:138560 ;
ChemSpider	141854 ;
KEGG	C03373 ;
MeSH	aminoimidazole+ribotide
PubChem CID	153;
CompTox Dashboard (EPA)	DTXSID60948494 ;
	InChI InChI=1S/C8H14N3O7P/c9-5-1-10-3-11(5)8-7(13)6(12)4(18-8)2-17-19(14,15)16/h1,3-4,6-8,12-13H,2,9H2,(H2,14,15,16)/t4-,6-,7-,8-/m1/s1 Key: PDACUKOKVHBVHJ-XVFCMESISA-N ;
	SMILES O=P(O)(O)OC[C@H]2O[C@@H](n1cncc1N)[C@H](O)[C@@H]2O;
Properties
Chemical formula	C8H14N3O7P
Molar mass	295.186 g/mol
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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	Infobox references

5'-Phosphoribosyl-5-aminoimidazole (or aminoimidazole ribotide) is an intermediate in the formation of purines. Thus, it is an intermediate in the adenine pathway, and is synthesized from 5'-phosphoribosylformylglycinamidine by AIR synthetase.[1]

References

Bhat, Balkrishen; Groziak, Michael P.; Leonard, Nelson J. (1990). "Nonenzymatic synthesis and properties of 5-aminoimidazole ribonucleotide (AIR). Synthesis of specifically 15N-labeled 5-aminoimidazole ribonucleoside (AIRs) derivatives". Journal of the American Chemical Society. 112 (12): 4891–4897. doi:10.1021/ja00168a039.

[1] Bhat, Balkrishen; Groziak, Michael P.; Leonard, Nelson J. (1990). "Nonenzymatic synthesis and properties of 5-aminoimidazole ribonucleotide (AIR). Synthesis of specifically 15N-labeled 5-aminoimidazole ribonucleoside (AIRs) derivatives". Journal of the American Chemical Society. 112 (12): 4891–4897. doi:10.1021/ja00168a039.

5-Aminoimidazole ribotide

See also

References