18-Hydroxycorticosterone

18-Hydroxycorticosterone
Identifiers
CAS Number	561-65-9 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:16485 ;
ChemSpider	10748 ;
ECHA InfoCard	100.008.384
MeSH	18-hydroxycorticosterone
PubChem CID	11222;
UNII	4U5T0O9SI3 ;
CompTox Dashboard (EPA)	DTXSID80897516 ;
	InChI InChI=1S/C21H30O5/c1-20-7-6-13(24)8-12(20)2-3-14-15-4-5-16(18(26)10-22)21(15,11-23)9-17(25)19(14)20/h8,14-17,19,22-23,25H,2-7,9-11H2,1H3/t14-,15-,16+,17-,19+,20-,21+/m0/s1 Key: HFSXHZZDNDGLQN-ZVIOFETBSA-N ; InChI=1/C21H30O5/c1-20-7-6-13(24)8-12(20)2-3-14-15-4-5-16(18(26)10-22)21(15,11-23)9-17(25)19(14)20/h8,14-17,19,22-23,25H,2-7,9-11H2,1H3/t14-,15-,16+,17-,19+,20-,21+/m0/s1 Key: HFSXHZZDNDGLQN-ZVIOFETBBO;
	SMILES O=C4\C=C2/[C@]([C@H]1[C@@H](O)C[C@@]3([C@@H](C(=O)CO)CC[C@H]3[C@@H]1CC2)CO)(C)CC4;
Properties
Chemical formula	C21H30O5
Molar mass	362.46 g/mol
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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	Infobox references

18-Hydroxycorticosterone is a derivative of corticosterone.

It serves as an intermediate in the synthesis of aldosterone by the enzyme aldosterone synthase in the zona glomerulosa:

Corticosteroid biosynthetic pathway in rat

References

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